What Is Sucralose? Safety, Risks & Alternatives

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E-Number	E955
FDA Status	FDA-approved in 1998 as a general-purpose sweetener. ADI: 5 mg/kg body weight/day. One of the most widely used artificia…
EFSA Status	EFSA approved with ADI of 15 mg/kg body weight/day. EFSA has not yet conducted a full re-evaluation incorporating the 20…
ADI	5 mg/kg body weight/day (FDA); 15 mg/kg body weight/day (EFSA)
Severity	Moderate Risk (6/10)

What Is Sucralose?

A zero-calorie artificial sweetener approximately 600 times sweeter than sucrose. Made by chlorinating sucrose (replacing three hydroxyl groups with chlorine atoms).

Mechanism of Action

Sucralose is largely unmetabolized and excreted unchanged. However, recent research (Schiffman et al., 2023) suggests that sucralose-6-acetate, a metabolite and trace contaminant, may be genotoxic in vitro. Other studies suggest potential effects on gut microbiome composition and glucose-insulin responses when consumed with carbohydrates.

Why People Avoid Sucralose

Regulatory Status

🇺🇸 FDA

FDA-approved in 1998 as a general-purpose sweetener. ADI: 5 mg/kg body weight/day. One of the most widely used artificial sweeteners globally.

🇪🇺 EFSA

EFSA approved with ADI of 15 mg/kg body weight/day. EFSA has not yet conducted a full re-evaluation incorporating the 2023 genotoxicity data.

Regulatory Timeline

Products Containing Sucralose (666 found in our database)

Product

Brand

Score

Sour Patch Kids Conversation Hearts

Frankford

0/100

PROTEIN PLANT POWERED TORTILLA WRAPS

Mission Foods Inc

0/100

SUNDRIED TOMATO BASIL TORTILLA WRAPS, TOMATO; BASIL

Mission Foods Inc

0/100

WHOLE WHEAT TORTILLA WRAPS, WHOLE WHEAT

Mission Foods Inc

0/100

MIO ENERGY, ICED COFFEE CONCENTRATE, ICED VANILLA JAVA

MIO ENERGY

0/100

THE ORIGINAL CHICKEN FLAVOR RAMEN NOODLE SOUP, CHICKEN

Nissin Foods USA Co Inc

0/100

CINNAMON FRENCH TOAST & SAUSAGE STICKS, CINNAMON

The Hillshire Brands Company

3/100

fit & protein milk shake cookie caramel

Gerlinéa

5/100

Ensure Max Protein nutrition shake

Ensure

5/100

BTE 50CL MONSTER PIPELIN PUNCH

Monster, Monster Energy, Monster Energy Company

5/100

Safer Alternatives

Scientific Sources

Frequently Asked Questions

What is Sucralose?: A zero-calorie artificial sweetener approximately 600 times sweeter than sucrose. Made by chlorinating sucrose (replacing three hydroxyl groups with chlorine atoms).
Is Sucralose safe?: Sucralose is FDA-approved in 1998 as a general-purpose sweetener. ADI: 5 mg/kg body weight/day. One of the most w. EFSA approved with ADI of 15 mg/kg body weight/day. EFSA has not yet conducted a full re-evaluation .
Where is Sucralose banned?: Sucralose is not currently banned in any major market according to our database.
What are alternatives to Sucralose?: Safer alternatives to Sucralose include: Stevia, Monk fruit extract, Erythritol, Allulose.
How can I avoid Sucralose?: Download CheckIt AI and scan any product's barcode or ingredient label. The app will flag Sucralose and suggest safer alternatives.
What foods contain Sucralose?: Sucralose is commonly found in: Splenda packets, Diet drinks, Protein bars, Sugar-free yogurt, Baked goods. Our database has flagged it in 666 products.
What are the side effects of Sucralose?: Concerns about Sucralose include: 2023 genotoxicity study on sucralose-6-acetate; Potential gut microbiome effects; Interaction with glucose metabolism when co-consumed with carbohydrates.
Is Sucralose natural or artificial?: Sucralose: Sucralose is largely unmetabolized and excreted unchanged. However, recent research (Schiffman et al., 2023) suggests that sucralose-6-acetate, a meta.

⚕️ This page provides ingredient information for educational purposes only. It is not medical advice. Consult a healthcare professional for personalized dietary guidance.

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📋 Cite This Data

APA

CheckIt AI. (2026). "What Is Sucralose? Safety, Risks & Alternatives | CheckIt AI". Climaverse PBC. Retrieved from https://getcheck.it/ingredients/sucralose

MLA

"What Is Sucralose? Safety, Risks & Alternatives | CheckIt AI." CheckIt AI, Climaverse PBC, 2026-03-08. https://getcheck.it/ingredients/sucralose.

HTML Embed

<a href="https://getcheck.it/ingredients/sucralose">What Is Sucralose? Safety, Risks & Alternatives | CheckIt AI — CheckIt AI</a>

BibTeX

@misc{checkit2026ingredientssucralose,
  title = {What Is Sucralose? Safety, Risks & Alternatives | CheckIt AI},
  author = {CheckIt AI},
  year = {2026},
  publisher = {Climaverse PBC},
  url = {https://getcheck.it/ingredients/sucralose},
  note = {Retrieved 2026-03-08}
}

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