Propylene Glycol is a solvent / humectant with 2 high-severity side effects. Found in 15 products in our database. FDA GRAS.
5
Known Side Effects
15
Products Contain It
2
High Severity
3
Safer Alternatives
What Is Propylene Glycol?
Propylene glycol is a synthetic solvent used in food, cosmetics, and as antifreeze. While 'generally recognized as safe' at low levels, it can cause skin reactions and serious effects at higher doses.
Also known as: E1520PG1,2-PropanediolMethylethylene glycol
Known Side Effects
ModerateSkin and eye irritation
ModerateAllergic contact dermatitis
High RiskCentral nervous system depression at high doses
High RiskLactic acidosis (rare, at high doses)
ModerateKidney and liver effects at high doses
Regulatory Status
🇺🇸 FDA Status
FDA GRAS. Used in food, pharmaceuticals, and cosmetics. Also used as antifreeze.
🇪🇺 EU Status
Legal with limits. E1520 approved as food additive.
Scientific References
WHO/JECFA evaluation setting ADI of 25mg/kg
Clinical reports of lactic acidosis from pharmaceutical PG exposure
Dermatological studies on contact allergy to propylene glycol
Products Containing Propylene Glycol (15 found)
These products were found to contain propylene glycol or its variants in our database of 26,000+ grocery products.
Propylene glycol can cause skin irritation, allergic dermatitis, and at high doses may cause central nervous system depression, lactic acidosis, and kidney/liver effects.
Is propylene glycol the same as antifreeze?
Propylene glycol is used in 'non-toxic' antifreeze. While it's less toxic than ethylene glycol, the same chemical is used in food products, which concerns many consumers.
⚕️ Disclaimer: This information is for educational purposes only and is not medical advice. Side effect data is compiled from published scientific studies and regulatory assessments. Always consult your healthcare provider for personalized guidance. Last updated: 2026-03-05.
Free · No credit card required · Works on iPhone & Android
📋 Cite This Data
APACheckIt AI. (2026). "Propylene Glycol Side Effects — Health Risks, FDA Status & Products | CheckIt AI". Climaverse PBC. Retrieved from https://getcheck.it/side-effects/propylene-glycol
MLA"Propylene Glycol Side Effects — Health Risks, FDA Status & Products | CheckIt AI." CheckIt AI, Climaverse PBC, 2026-03-05. https://getcheck.it/side-effects/propylene-glycol.
HTML Embed<a href="https://getcheck.it/side-effects/propylene-glycol">Propylene Glycol Side Effects — Health Risks, FDA Status & Products | CheckIt AI — CheckIt AI</a>
BibTeX@misc{checkit2026sideeffectspropyleneglycol,
title = {Propylene Glycol Side Effects — Health Risks, FDA Status & Products | CheckIt AI},
author = {CheckIt AI},
year = {2026},
publisher = {Climaverse PBC},
url = {https://getcheck.it/side-effects/propylene-glycol},
note = {Retrieved 2026-03-05}
}