What Is Propylene Glycol? Safety, Risks & Alternatives

⚡ Quick Facts

E-NumberE1520
FDA StatusFDA classifies propylene glycol as GRAS (21 CFR 184.1666) for direct addition to food at levels not to exceed 5% of tota…
EFSA StatusEFSA established a group ADI of 25 mg/kg body weight/day for propylene glycol (E 1520) in 2018. EFSA noted that dietary …
ADI25 mg/kg body weight/day (EFSA group ADI)
SeverityModerate Risk (6/10)

What Is Propylene Glycol?

A synthetic organic compound that is a colorless, nearly odorless, slightly sweet liquid. It belongs to the same chemical class as ethylene glycol (antifreeze) but is considered significantly less toxic. Propylene glycol is used as a humectant, solvent, and preservative in foods, pharmaceuticals, cosmetics, and e-cigarette liquids. It is also used as an antifreeze in food-grade applications.

Mechanism of Action

Propylene glycol absorbs water and helps maintain moisture in food products. It acts as a solvent for food colors, flavors, and antioxidants that are not soluble in water. In the body, it is metabolized in the liver via alcohol dehydrogenase to lactic acid and pyruvic acid. At high doses, it can cause hyperosmolality, lactic acidosis, and CNS depression. Cases of toxicity have been reported with IV medications containing propylene glycol as a solvent.

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Why People Avoid Propylene Glycol

Regulatory Status

🇺🇸 FDA

FDA classifies propylene glycol as GRAS (21 CFR 184.1666) for direct addition to food at levels not to exceed 5% of total food weight. It is approved as an emulsifier, humectant, solvent, and dough strengthener. Also approved for use in cosmetics and pharmaceuticals.

🇪🇺 EFSA

EFSA established a group ADI of 25 mg/kg body weight/day for propylene glycol (E 1520) in 2018. EFSA noted that dietary exposure can exceed the ADI in high consumers, particularly children. Recommended reduced maximum use levels in some food categories.

Regulatory Timeline

1942 Propylene glycol first used as a substitute for glycerol during wartime shortages
1973 FDA affirms GRAS status for food use
2018 EFSA re-evaluates and lowers recommended maximum use levels

📊 Top Categories Containing Propylene Glycol

Ice Cream & Frozen Yogurt 43Cheveux 10Cakes 9Cupcakes 9Snack Cakes 9 8
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Products Containing Propylene Glycol (198 found in our database)

#ProductBrandScore
1King Soopers, City Market, Give Thanks Seasonal Chocolate CakeThe Kroger Co.0/100
2MAINE BLUEBERRY BELGIAN WAFFLE CONE ICE CREAM, MAINE BLUEBERRY BELGIAN WAFFLE CONEThe Kroger Co.0/100
3BLACK RASPBERRY DARK CHOCOLATE CHUNK ICE CREAM, BLACK RASPBERRY DARK CHOCOLATE CHUNKThe Kroger Co.2/100
4BLACK RASPBERRY DARK CHOCOLATE CHUNK ICE CREAM, BLACK RASPBERRY DARK CHOCOLATE CHUNKThe Kroger Co.2/100
5Denali Mint Moose Tracks Ice CreamPrivate Selection3/100
6VANILLA BAR WITH NESTLE CRUNCH COATING FROZEN DAIRY DESSERT BAR, VANILLABig Drum7/100
7NESTLE, SKINNY COW, ICE CREAM SANDWICHES, VANILLA & CHOCOLATE, VANILLA & CHOCOLATEDreyer's Grand Ice Cream Inc.7/100
8PRIVATE SELECTION, ENGLISH TOFFEE CARAMEL ICE CREAMThe Kroger Co.7/100
9DENALI EXTREME MOOSE TRACKS ICE CREAM, DENALI EXTREME MOOSE TRACKSThe Kroger Co.7/100
10ICE CREAMThe Kroger Co.7/100

Showing top 10 of 198 products. Download CheckIt AI to scan any product.

Average safety score for products containing Propylene Glycol: 56/100

Safer Alternatives


Vegetable glycerin

Honey

Maple syrup

Sorbitol (for moisture retention)

Scientific Sources

  1. EFSA (2018). Re-evaluation of propylene glycol (E 1520) as a food additive. EFSA Journal, 16(4), 5235
  2. FDA (21 CFR 184.1666). Propylene glycol — GRAS substances
  3. Lim et al. (2014). Propylene glycol toxicity: A review. Clinical Toxicology, 52(6), 513-520

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Frequently Asked Questions

What is Propylene Glycol?
A synthetic organic compound that is a colorless, nearly odorless, slightly sweet liquid. It belongs to the same chemical class as ethylene glycol (antifreeze) but is considered significantly less toxic. Propylene glycol is used as a humectant, solvent, and preservative in foods, pharmaceuticals, cosmetics, and e-cigarette liquids. It is also used as an antifreeze in food-grade applications.
Is Propylene Glycol safe?
Propylene Glycol is FDA classifies propylene glycol as GRAS (21 CFR 184.1666) for direct addition to food at levels not . EFSA established a group ADI of 25 mg/kg body weight/day for propylene glycol (E 1520) in 2018. EFSA.
Where is Propylene Glycol banned?
Propylene Glycol is not currently banned in any major market according to our database.
What are alternatives to Propylene Glycol?
Safer alternatives to Propylene Glycol include: Vegetable glycerin, Honey, Maple syrup, Sorbitol (for moisture retention).
How can I avoid Propylene Glycol?
Download CheckIt AI and scan any product's barcode or ingredient label. The app will flag Propylene Glycol and suggest safer alternatives.
What foods contain Propylene Glycol?
Propylene Glycol is commonly found in: Ice cream, Salad dressings, Soft drinks, Cake mixes, Food coloring, Flavoring extracts, Pharmaceutical syrups, E-cigarette liquid. Our database has flagged it in 198 products.
What are the side effects of Propylene Glycol?
Concerns about Propylene Glycol include: Same chemical class as ethylene glycol (antifreeze) — causes consumer concern; EFSA found dietary exposure can exceed ADI in children; Can cause contact dermatitis in sensitive individuals.
Is Propylene Glycol natural or artificial?
Propylene Glycol: Propylene glycol absorbs water and helps maintain moisture in food products. It acts as a solvent for food colors, flavors, and antioxidants that are .
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⚕️ This page provides ingredient information for educational purposes only. It is not medical advice. Consult a healthcare professional for personalized dietary guidance. This information is for educational purposes only. Consult a healthcare professional for personalized dietary advice.

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📋 Cite This Data
APACheckIt AI. (2026). "What Is Propylene Glycol? Safety, Risks & Alternatives | CheckIt AI". Climaverse PBC. Retrieved from https://getcheck.it/ingredients/propylene-glycol
MLA"What Is Propylene Glycol? Safety, Risks & Alternatives | CheckIt AI." CheckIt AI, Climaverse PBC, 2026-04-17. https://getcheck.it/ingredients/propylene-glycol.
HTML Embed<a href="https://getcheck.it/ingredients/propylene-glycol">What Is Propylene Glycol? Safety, Risks & Alternatives | CheckIt AI — CheckIt AI</a>
BibTeX@misc{checkit2026ingredientspropyleneglycol, title = {What Is Propylene Glycol? Safety, Risks & Alternatives | CheckIt AI}, author = {CheckIt AI}, year = {2026}, publisher = {Climaverse PBC}, url = {https://getcheck.it/ingredients/propylene-glycol}, note = {Retrieved 2026-04-17} }